The Ordinary Argireline vs. Multi-Peptide + HA

Editorial draft · Scientific review pending Updated 2026-10-20

The Ordinary

Argireline Solution 10%

30 mL · Facial serum

$9.70USD · Recorded 2026-10-19

The Ordinary

Multi-Peptide + HA Serum

30 mL · Facial serum

$19.90USD · Recorded 2026-10-19

Two formulas. A closer look at what matters. Change products

THE SHORT VERSION

What matters in 30 seconds.

The key findings, without the chemistry lesson.

What is documented?

Both labels list Acetyl Hexapeptide-8. Multi-Peptide + HA records additional selected peptides.[1][2]

Manufacturer labels

See ingredient differences

What does it mean for your purchase?

Argireline has the lower recorded 30 mL price. Shared ingredients do not establish that buying both adds a benefit.[1][2]

Recorded prices · not a performance ranking

Understand the price

What has not been demonstrated?

This label comparison does not establish which finished serum works better or is safer. Individual tolerance and additional benefit cannot be predicted from the selected names.

Editorial interpretation of label information

Check the evidence

Before you choose: label facts do not establish which finished formula is safer or more effective. If you have a confirmed ingredient allergy, check the full label before buying.

Understand the evidence

SIDE BY SIDE

Ingredients, price and the gaps.

Compare selected label facts. Tap an ingredient to understand its name.

Show only differencesAll recorded details · No product rankings

Compare recorded facts side by side. Missing information is not a negative rating.

Peptide serum label comparison: The Ordinary and The Ordinary
Compare the detailsTwo products. The same questions.	A The OrdinaryArgireline Solution 10%	B The OrdinaryMulti-Peptide + HA Serum
Product basics
Presentation	30 mL	30 mL
Format	Water-based serum	Water-based serum
How the brand says to use it	The brand directs a few drops in the morning and evening, on unbroken skin, and advises patch testing. Read its current compatibility exclusions before combining with other products.Manufacturer directions, not a personalized routine.	The brand directs a few drops in the morning and evening, on unbroken skin, and advises patch testing. Read its current compatibility exclusions before combining with other products.Manufacturer directions, not a personalized routine.
Price & value
Recorded price	$9.70 USDPrice recorded 2026-10-19Excludes tax and shipping.	$19.90 USDPrice recorded 2026-10-19Excludes tax and shipping.
Price per mL	$0.32 / mL	$0.66 / mL
What it contains and what it means
Peptides, explained Peptides are small chains of the building blocks used in proteins. Their names identify ingredients, not quality scores. Open an explanation to learn what each one means.	Acetyl Hexapeptide-8 A peptide studied for the appearance of expression lines around the eyes. Full guide INGREDIENT, EXPLAINED Acetyl Hexapeptide-8 A peptide studied for the appearance of expression lines around the eyes. Type of support: Ingredient study Editorial draft · Qualified scientific review pending. What it is A synthetic peptide investigated under the name Argireline. The study concerns a specific preparation, not every product listing this ingredient. Wang et al. (2013): randomized study of Argireline and eye-area lines Why it is used Studied as a cosmetic ingredient for reducing the appearance of eye-area lines. Wang et al. (2013): randomized study of Argireline and eye-area lines What the evidence means A four-week randomized placebo-controlled trial enrolled 60 Chinese participants (3:1 allocation) and reported improved eye-area wrinkle measures. The inspected abstract does not establish results for the retail serums here or long-term benefit. A 24-hour laboratory skin-penetration study is a different kind of evidence, not a clinical efficacy trial. Wang et al. (2013): randomized study of Argireline and eye-area lines In vitro skin penetration of acetyl hexapeptide-8 from a cosmetic formulation Precautions and possible reactions The 2025 safety panel concluded safe cosmetic use up to 0.005%; above that, it found insufficient data to determine safety. This is not evidence of harm above that amount. The pure-peptide concentrations in these compared serums are not verified, so this assessment cannot certify either bottle. A commercial blend percentage is not automatically the pure-peptide percentage. Cosmetics can cause irritation or allergic reactions. Check the full ingredient list and follow product directions. Acetyl Hexapeptide-8 Amide: cosmetic safety assessment (2025) Allergens in cosmetics: reactions and consumer precautions What this means for your comparison There is human research on a preparation of this ingredient. That is different from a direct test of this serum. Sources checked 2026-10-20. Ingredient information is separate from testing a finished serum. Read the full ingredient guide Selected label peptides, not the complete INCI list. Other peptides and non-peptide ingredients may be omitted. See the manufacturer for the full formula.	Acetyl Hexapeptide-8 A peptide studied for the appearance of expression lines around the eyes. Full guide INGREDIENT, EXPLAINED Acetyl Hexapeptide-8 A peptide studied for the appearance of expression lines around the eyes. Type of support: Ingredient study Editorial draft · Qualified scientific review pending. What it is A synthetic peptide investigated under the name Argireline. The study concerns a specific preparation, not every product listing this ingredient. Wang et al. (2013): randomized study of Argireline and eye-area lines Why it is used Studied as a cosmetic ingredient for reducing the appearance of eye-area lines. Wang et al. (2013): randomized study of Argireline and eye-area lines What the evidence means A four-week randomized placebo-controlled trial enrolled 60 Chinese participants (3:1 allocation) and reported improved eye-area wrinkle measures. The inspected abstract does not establish results for the retail serums here or long-term benefit. A 24-hour laboratory skin-penetration study is a different kind of evidence, not a clinical efficacy trial. Wang et al. (2013): randomized study of Argireline and eye-area lines In vitro skin penetration of acetyl hexapeptide-8 from a cosmetic formulation Precautions and possible reactions The 2025 safety panel concluded safe cosmetic use up to 0.005%; above that, it found insufficient data to determine safety. This is not evidence of harm above that amount. The pure-peptide concentrations in these compared serums are not verified, so this assessment cannot certify either bottle. A commercial blend percentage is not automatically the pure-peptide percentage. Cosmetics can cause irritation or allergic reactions. Check the full ingredient list and follow product directions. Acetyl Hexapeptide-8 Amide: cosmetic safety assessment (2025) Allergens in cosmetics: reactions and consumer precautions What this means for your comparison There is human research on a preparation of this ingredient. That is different from a direct test of this serum. Sources checked 2026-10-20. Ingredient information is separate from testing a finished serum. Read the full ingredient guide Palmitoyl Tripeptide-1 A skin-conditioning peptide used in blends marketed for the appearance of wrinkles. Full guide INGREDIENT, EXPLAINED Palmitoyl Tripeptide-1 A skin-conditioning peptide used in blends marketed for the appearance of wrinkles. Type of support: Supplier description Editorial draft · Qualified scientific review pending. What it is A peptide with three amino-acid units and an attached fatty-acid part. The added part distinguishes its ingredient name. Peptide ingredient identities, functions and safety assessment (2018) Why it is used Croda includes it in Matrixyl 3000, an ingredient blend marketed for wrinkle appearance. This does not confirm a branded blend or its dose in this serum. Matrixyl 3000: supplier description and ingredient names What the evidence means The supplier describes a blend, not an independent test of this ingredient alone in The Ordinary serum. Matrixyl 3000: supplier description and ingredient names Precautions and possible reactions A safety review addresses reported cosmetic uses, not every possible formula or individual reaction. Cosmetics can cause irritation or allergic reactions. Check the full ingredient list and follow product directions. Peptide ingredient identities, functions and safety assessment (2018) Allergens in cosmetics: reactions and consumer precautions What this means for your comparison A peptide blend’s claims cannot be assigned to this ingredient alone or used to rank these two serums. Sources checked 2026-10-19. Ingredient information is separate from testing a finished serum. Read the full ingredient guide Palmitoyl Tetrapeptide-7 A skin-conditioning peptide used in blends marketed for the appearance of wrinkles. Full guide INGREDIENT, EXPLAINED Palmitoyl Tetrapeptide-7 A skin-conditioning peptide used in blends marketed for the appearance of wrinkles. Type of support: Supplier description Editorial draft · Qualified scientific review pending. What it is A peptide with four amino-acid units and an attached fatty-acid part. The added part distinguishes its ingredient name. Peptide ingredient identities, functions and safety assessment (2018) Why it is used Croda includes it in Matrixyl 3000, an ingredient blend marketed for wrinkle appearance. This does not confirm a branded blend or its dose in this serum. Matrixyl 3000: supplier description and ingredient names What the evidence means The supplier describes a blend, not an independent test of this ingredient alone in The Ordinary serum. Matrixyl 3000: supplier description and ingredient names Precautions and possible reactions A safety review addresses reported cosmetic uses, not every possible formula or individual reaction. Cosmetics can cause irritation or allergic reactions. Check the full ingredient list and follow product directions. Peptide ingredient identities, functions and safety assessment (2018) Allergens in cosmetics: reactions and consumer precautions What this means for your comparison A peptide blend’s claims cannot be assigned to this ingredient alone or used to rank these two serums. Sources checked 2026-10-19. Ingredient information is separate from testing a finished serum. Read the full ingredient guide Palmitoyl Tripeptide-38 A peptide associated with the commercial blend name Matrixyl synthe’6. Full guide INGREDIENT, EXPLAINED Palmitoyl Tripeptide-38 A peptide associated with the commercial blend name Matrixyl synthe’6. Type of support: Label information Editorial draft · Qualified scientific review pending. What it is This ingredient name appears on the recorded Matrixyl, Multi-Peptide + HA and Power Peptides labels. Matrixyl 10% + HA — US manufacturer label and 30 mL offer Multi-Peptide + HA Serum — US manufacturer label and 30 mL offer Power Peptides — US manufacturer label and 30 mL offer Why it is used The brands place it in blends marketed for the appearance of lines. This does not isolate its contribution to a finished serum. Matrixyl 10% + HA — US manufacturer label and 30 mL offer Multi-Peptide + HA Serum — US manufacturer label and 30 mL offer Power Peptides — US manufacturer label and 30 mL offer What the evidence means The recorded support is manufacturer information about labels and ingredient systems. It does not establish how well this ingredient alone works in these finished serums. Matrixyl 10% + HA — US manufacturer label and 30 mL offer Multi-Peptide + HA Serum — US manufacturer label and 30 mL offer Power Peptides — US manufacturer label and 30 mL offer Precautions and possible reactions An ingredient-specific side-effect rate is not established by these sources. Check the complete product label and follow its current instructions. Cosmetics can cause irritation or allergic reactions. Check the full ingredient list and follow product directions. Matrixyl 10% + HA — US manufacturer label and 30 mL offer Multi-Peptide + HA Serum — US manufacturer label and 30 mL offer Power Peptides — US manufacturer label and 30 mL offer Allergens in cosmetics: reactions and consumer precautions What this means for your comparison Recognize the exact ingredient name, then consider the whole product. Neither its number nor a blend percentage tells us which serum will work better for you. Sources checked 2026-10-19. Ingredient information is separate from testing a finished serum. Read the full ingredient guide Selected label peptides, not the complete INCI list. Other peptides and non-peptide ingredients may be omitted. See the manufacturer for the full formula.
How much of each ingredient? A formula is the whole mix. A blend percentage does not tell us the amount of every ingredient.	The product name describes an Argireline solution at 10%. Do not read it as 10% pure Acetyl Hexapeptide-8 or compare it directly with another brand’s blend percentage.Manufacturer disclosure; not independently measured.Individual amounts not verified	Several peptides are listed, but their separate amounts are not disclosed. HA means hyaluronic acid; it is not another peptide.Manufacturer disclosure; not independently measured.Individual amounts not verified
Sources & limits
What we still cannot know	Not established Complete ingredient list in this catalog Independent comparative effectiveness	Not established Complete ingredient list in this catalog Independent comparative effectiveness
Label source	The Ordinary manufacturer label Label checked 2026-10-19Label checked; not a clinical review.	The Ordinary manufacturer label Label checked 2026-10-20Label checked; not a clinical review.

Prices are dated USD observations. Ingredient selections are incomplete; matching names do not establish equivalent formulas or results.

What do the label differences mean?Exact names, disclosures and cost limits

A commercial name and an ingredient name can refer to related information

Look for Acetyl Hexapeptide-8 on the label. The Argireline name is not a separate extra peptide in this comparison.[1][2]

More names do not guarantee more benefit

Multi-Peptide + HA lists other selected peptides. This catalog does not establish whether adding them produces better results than the Argireline solution.[1][2]

Avoid buying two products just because their names differ

The overlap is useful when researching a purchase. It does not prove that combining both products adds a benefit, or that one can replace the other for every person.[1][2]

Documented differences

Acetyl Hexapeptide-8 is the exact shared label name. Argireline is a commercial name associated with this peptide. The record does not establish equivalent individual concentrations across these serums.[1][2]

Use this comparison for your decision

If you recognize Argireline but not the INCI name

Look for Acetyl Hexapeptide-8. Both records list it, while the broader blend records additional selected peptides.[1][2]

If you are considering buying both

The shared name is a reason to inspect overlap and your intended purchase. It does not establish that using both adds benefit, or that one replaces the other for everyone.[1][2]

LABEL FACTS AND THEIR LIMITS

What the sources tell us.

What do the source labels mean?

Human studies describe what happened in their participants and tested preparation. Laboratory studies examine a model, not clinical results in shoppers. Case reports describe individual events, not how often they occur.

Safety assessments review specified uses and concentrations. Manufacturer labels identify recorded product facts. Neither is a guarantee of results or individual tolerance. Source type is not a quality score.

What the labels document

Source type: Manufacturer label

Both labels list Acetyl Hexapeptide-8. Multi-Peptide + HA records additional selected peptides.[1][2]

Read the evidence and what it means

Source type: Manufacturer label

Amounts: disclosure is not measurement

Source type: Manufacturer label

Headline disclosures do not give verified individual amounts for every selected peptide.[1][2]

Read the evidence and what it means

Source type: Manufacturer label

The Ordinary: The product name describes an Argireline solution at 10%. Do not read it as 10% pure Acetyl Hexapeptide-8 or compare it directly with another brand’s blend percentage.[1]

Source type: Manufacturer label

The Ordinary: Several peptides are listed, but their separate amounts are not disclosed. HA means hyaluronic acid; it is not another peptide.[2]

What these sources cannot establish

Editorial interpretation

Recorded labels do not establish a clinical winner or years of safety for these complete formulas.

Read the evidence and what it means

Editorial interpretation

This is a comparison of selected label information, not a complete clinical efficacy or safety review. Missing product-level evidence here is not evidence that either product is harmful or ineffective.

Cost and the exact presentation

Editorial interpretation

Argireline has the lower recorded 30 mL price. Shared ingredients do not establish that buying both adds a benefit.

Read the evidence and what it means

Editorial interpretation

The catalog shows selected label peptides, not complete formulas. Individual concentrations may be undisclosed. No independent head-to-head effectiveness or individual tolerance is established here. This editorial draft awaits human review.

What is recorded on the labels?

Source type: Manufacturer label

The paired manufacturer sources document the recorded product names and selected ingredients. These lists are incomplete, formulas may change, and manufacturer information is not independent clinical corroboration.[1][2]

Manufacturer links establish ingredient presence only. Scientific references support the research statements above. Formulas can change; check your purchased packaging.

A LITTLE MORE CLARITY

Questions about these products

Is Argireline listed as Acetyl Hexapeptide-8?

Acetyl Hexapeptide-8 is the peptide name recorded on the Argireline solution label and also on Multi-Peptide + HA. Commercial and INCI names provide different label context.[1][2]

Does the 10% solution contain more of that peptide than Multi-Peptide + HA?

The recorded information does not establish separately comparable pure-peptide amounts. Do not use the printed solution percentage to infer an undisclosed amount in the broader blend.[1][2]

Check the original sources

Research and safety assessments are separate from manufacturer labels.

How this comparison was preparedScope, review status and limitations

What we cannot tell from the label

Read our methodology

CHECK THE CURRENT OFFER

Where to buy

Check the exact size, current price and shipping at the manufacturer.

The OrdinaryArgireline Solution 10%30 mL · $9.70 USD · Recorded 2026-10-19

View Argireline Solution 10% · 30 mL at The Ordinary Select the 30 mL option on the retailer’s page. Confirm the current price before checkout.

The OrdinaryMulti-Peptide + HA Serum30 mL · $19.90 USD · Recorded 2026-10-19

View Multi-Peptide + HA Serum · 30 mL at The Ordinary Select the 30 mL option on the retailer’s page. Confirm the current price before checkout.

No affiliate partnerships are active. Manufacturer links are ordinary links; we do not earn commissions from them. Recorded prices exclude tax and shipping and may have changed.

References

Manufacturer labelArgireline Solution 10% — US manufacturer label and 30 mL offer
The Ordinary · Reference checked 2026-10-19
Evidence and limitations for reference 1
What this supports here
Supports the wording Argireline Solution 10% and the brand’s ingredient disclosure.
What it cannot establish
This product name is not evidence that the product is the formulation used in a particular academic study.
Commercial context and disclosures
Published by the seller and manufacturer.
What we inspected
Public US product page
↩ 1 ↩ 2 ↩ 3 ↩ 4 ↩ 5 ↩ 6 ↩ 7 ↩ 8 ↩ 9 ↩ 10 ↩ 11 ↩ 12 ↩ 13 ↩ 14 ↩ 15 ↩ 16 ↩ 17
Manufacturer labelMulti-Peptide + HA Serum — US manufacturer label and 30 mL offer
The Ordinary · Reference checked 2026-10-20
Evidence and limitations for reference 2
What this supports here
Supports the selected ingredient names and identity of Multi-Peptide + HA.
What it cannot establish
The checked label does not supply a separate amount for every peptide or independent comparative outcomes.
Commercial context and disclosures
Published by the seller and manufacturer.
What we inspected
Public US product page
↩ 1 ↩ 2 ↩ 3 ↩ 4 ↩ 5 ↩ 6 ↩ 7 ↩ 8 ↩ 9 ↩ 10 ↩ 11 ↩ 12 ↩ 13 ↩ 14 ↩ 15 ↩ 16 ↩ 17